2007

Zhou T, Xu L, Dey B, Hessell AJ, Van Ryk D, Xiang SH, Yang X, Zhang MY, Zwick MB, Arthos J, Burton DR, Dimitrov DS, Sodroski J, Wyatt R, Nabel GJ, Kwong PD.Structural definition of a conserved neutralization epitope on HIV-1 gp120. Nature 2007, 445: 732-7 PDF

Blumenthal R, Dimitrov DS. Targeting the Sticky Fingers of HIV-1.Cell 2007, 129: 243-5 PDF

Bossart KN, McEachern JA, Hickey AC, Choudhry V, Dimitrov DS, Eaton BT, Wang LF.Neutralization assays for differential henipavirus serology using Bio-Plex protein array systems. J. Virol. Methods 2007, 142: 29-40 PDF

Choudhry V, Zhang MY, Sidorov IA, Louis JM, Harris I, Dimitrov AS, Bouma P, Cham F, Choudhary A, Rybak SM, Fouts T, Montefiori DC, Broder CC, Quinnan GV, Dimitrov DS. Cross-reactive HIV-1 neutralizing monoclonal antibodies selected by screening of an immune human phage library against an envelope glycoprotein (gp140) isolated from a patient (R2) with broadly HIV-1 neutralizing antibodies. Virology 2007, 363: 79-90 PDF

JimŽnez-Baranda S, G—mez-Mout—n C, Rojas A, Mart’nez-Prats L, Mira E, Ana Lacalle R, Valencia A, Dimitrov DS, Viola A, Delgado R, Mart’nez-A C, Ma–es S. Filamin-A regulates actin-dependent clustering of HIV receptors.Nat Cell Biol. 2007, 9(7): 838-46 PDF

Prabakaran P, Dimitrov AS, Fouts TR, Dimitrov DS. Structure and Function of the HIV Envelope Glycoprotein as Entry Mediator, Vaccine Immunogen, and Target for Inhibitors. Adv. Pharmacol. 2007, 55: 33-97 PDF

Dimitrov DS, Wang LF. In utero transmission of nipah virus: role played by pregnancy and vertical transmission in henipavirus epidemiology.J. Infect. Dis. 2007, 196: 807-9 PDF

Zhu Z, Chakraborti S, He Y, Roberts A, Sheahan T, Xiao X, Hensley LE, Prabakaran P, Rockx B, Sidorov IA, Corti D, Vogel L, Feng Y, Kim JO, Wang LF, Baric R, Lanzavecchia A, Curtis KM, Nabel GJ, Subbarao K, Jiang S, Dimitrov DS. Potent cross-reactive neutralization of SARS coronavirus isolates by human monoclonal antibodies. Proc. Natl. Acad. Sci. U.S.A. 2007, 104: 12123-8 PDF

Zhang, M.-Y., Dimitrov D.S. Novel approaches for identification of broadly cross-reactive hiv-1 neutralizing human monoclonal antibodies and improvement of their potency. Current Pharmaceutical Design 2007, 13: 203-212 PDF

2006

Prabakaran P., Gan J., Feng Y., Zhu Z., Choudhry V., Xiao X., Ji X., Dimitrov D.S. Structure of severe acute respiratory syndrome coronavirus receptor-binding domain complexed with neutralizing antibody. J. Biol. Chem., 2006, 281(23): 15829-15836 PDF

Zhang, M.Y., Vu, B., Huang, C.C., Sidorov, I., Choudhly, V., Kwong, P.D., Dimitrov, D.S. Identification of human monoclonal antibodies specific for CCR5 from an antibody library derived from HIV-infected long-term non-progressors. Retrovirology, 2006, 3 Suppl 1: S61. PDF

Sidorov, I. A., Prabakaran, P., Dimitrov, D. S. Non-covalent conjugation of nanoparticles to antibodies via electrostatic interactions - a computational model, J. Comp. & Theor. Nanosci. 2006 (in press) PDF

Dimitrov, D.S., Sidorov, I.A., and Kasabov, N. Computational Biology. In Rieth, M. and Schommers, W. (Eds.): Handbook of Theoretical and Computational Nanotechnology. Stevenson Ranch, CA, American Scientific Publishers, 2006, pp. 1-46 PDF

Zhang, M.-Y., Choudhry, V., Sidorov, I.A., Tenev, V., Vu, B.K., Choudhary, A., Lu, H., Stiegler, G.M., Katinger, H.W.D., Jiang, S., Broder, C.C., Dimitrov D.S. Selection of a novel gp41-specific HIV-1 neutralizing human antibody by competitive antigen panning. J. Immunol. Meth. 2006, 317: 21-30 PDF

Sidorov, I. A., Dimitrov, D. S. Nanobiology Think Tank: Computational and theoretical nanoscience is taking off at the National Cancer Institute, J. Comp. & Theor. Nanosci. 2006, 3(5): 599-602 PDF

Feng, Y., Yuan, J.H., Maloid, S.C., Fisher, R., Copeland, T.D., Longo, D.L., Conrads, T.P., Veenstra, T.D., Ferris, A., Hughes, S., Dimitrov, D.S., Ferris, D.K. Polo-like kinase 1-mediated phosphorylation of the GTP-binding protein Ran is important for bipolar spindle formation. Biochem. Biophys. Res. Comm. 2006, 349(1): 144-152 PDF

Choudhry V., Zhang M.-Y., Harris I., Sidorov I.A., Vu B., Dimitrov A.S., Fouts T., Dimitrov D.S. Increased efficacy of HIV-1 neutralization by antibodies at low CCR5 surface concentration. Biochem. Biophys. Res. Comm. 2006, 348(3): 1107-1115 PDF

Dimitrov, D.S. Interactions of antibody-conjugated nanoparticles with biological surfaces. Colloids and Surfaces A: Physicochemical and Engineering Aspects 2006, 282-283: 8-10 PDF

Choudhry, V., Zhang, M.Y., Dimitrova, D., Prabakaran, P., Dimitrov, A.S., Fouts, T.R., Dimitrov, D.S. Antibody-based inhibitors of HIV infection. Expert. Opin. Biol. Ther. 2006, 6(5): 523-531 PDF

Sidorov, I.A., Blumenthal, R., Dimitrov, D.S. A model of drug delivery to normal and cancer cells by antibody-targeted nanoliposomes. J. Comp. & Theor. Nanosci. 2006, 3: 405-411 PDF

Feng, Y., Zhu, Z., Xiao, X., Choudhry, V., Barrett, J.C., Dimitrov, D.S. Novel human monoclonal antibodies to insulin-like growth factor (IGF)-II that potently inhibit the IGF receptor type I signal transduction function. Mol. Cancer Ther. 2006, 5(1): 114-120 PDF

Zhu, Z., Dimitrov, A.S., Chakraborti, S., Dimitrova, D., Xiao, X., Broder, C.C., Dimitrov, D.S. Development of human monoclonal antibodies against diseases caused by emerging and biodefense-related viruses. Expert. Rev. Anti. Infect. Ther. 2006, 4(1): 57-66 PDF

Prabakaran, P., Gan, J., Wu, Y.-Q., Zhang, M.-Y., Dimitrov, D.S., Ji, X. Structural mimicry of CD4 by a cross-reactive HIV-1 neutralizing antibody with CDR-H2 and H3 containing unique motifs. J. Mol. Biol. 2006, 357(1): 82-99 PDF

Patton G.W., Stephens R., Sidorov I.A., Xiao X., Dimitrov D.S., Shoemaker R.H., Tudor G. Transcriptomic response to differentiation induction, BMC Bioinformatics 2006, 7: 81-85 PDF

Di Mascio, M., Sereti, I., Matthews, L.T., Natarajan, V., Adelsberger, J., Lempicki, R., Yoder, C., Jones, E., Chow, C., Metcalf, J.A., Sidorov, I.A., Dimitrov, D.S., Polis, M.A., Kovacs, J.A. Naive T cell dynamics in HIV-1 infection: effects of HAART provide insights into the mechanisms of naive T cell depletion. J. Virol. 2006, 80(6): 2665-2674 PDF

Zhu, Z., Dimitrov, A.S., Bossart, K.N., Crameri, G., Bishop, K.A., Choudhry, V., Mungall, B.A., Feng, Y.R., Choudhary, A., Zhang, M.Y., Feng, Y., Wang, L.F., Xiao, X., Eaton, B.T., Broder, C.C., Dimitrov, D.S. Potent neutralization of hendra and nipah viruses by human monoclonal antibodies. J. Virol. 2006, 80(2): 891-899 PDF

2005

Kasabov, N., Sidorov, I.A., Dimitrov, D.S. Computational intelligence, bioinformatics and computational biology: a brief overview of methods, problems and perspectives J. Comp. & Theor. Nanosci. 2005, 2(4): 473-491 PDF

Huang, C.C., Tang, M., Zhang, M.Y., Majeed, S., Montabana, E., Stanfield, R.L., Dimitrov, D.S., Korber, B., Sodroski, J., Wilson, I.A., Wyatt, R., Kwong, P.D. Structure of a V3-containing HIV-1 gp120 core. Science 2005, 310(5750): 1025-1028 PDF

Chakraborti, S., Prabakaran, P., Xiao, X., Dimitrov, D.S. The SARS coronavirus S glycoprotein receptor binding domain: fine mapping and functional characterization. Virol J. 2005, 2(1): 73-82 PDF

Bonaparte, M.I., Dimitrov, A.S., Bossart, K.N., Crameri, G., Mungall, B.A., Bishop, K.A., Choudhry, V., Dimitrov, D.S., Wang, L.F., Eaton, B.T., Broder, C.C. Ephrin-B2 ligand is a functional receptor for Hendra virus and Nipah virus. Proc. Natl. Acad. Sci. 2005, 102(30): 10652-10657 PDF

Xiao, X., Sidorov, I.A., Gee, J., Lempicki, R.A., Dimitrov, D.S. Retinoic acid-induced downmodulation of telomerase activity in human cancer cells. Exp. Mol. Pathol. 2005, 79: 108-117 PDF

Kovacs, J.A., Lempicki, R.A., Sidorov, I.A., Adelsberger, J.W., Sereti, I., Sachau, W., Kelly, G., Metcalf, J.A., Davey, R.T., Falloon, J., Polis, M.A., Tavel, J., Stevens, R., Lambert, L., Hosack, D.A., Issaq, H.J., Fox, S.D., Leitman, S., Baseler, M.W., Masur, H., Di Mascio, M., Dimitrov, D.S., and Lane, H.C. Induction of prolonged survival of CD4+ T lymphocytes by intermittent IL-2 therapy in patients with HIV infection. J. Clin. Invest. 2005, 115: 2139-2148 PDF

Dimitrov, D.S. From SDS gels to supercomputers and more: highlights of the symposium honoring the scientific achievements of Dr. Jacob Maizel, Jr. CCR Frontiers in Science 4: 10-11, 2005 PDF

Zhang, M.-Y., Choudhry, V., Xiao, X., Dimitrov, D.S. Human monoclonal antibodies to the S glycoprotein and related proteins as potential therapeutics for SARS. Current Opinion in Molecular Therapeutics 7: 151-156, 2005 PDF

Dimitrov, D.S. Identification of novel human monoclonal antibodies to viral envelope glycoproteins and cancer-associated antiogens and improvement of their efficacy. CCR Frontiers in Science 4: 3-4, 2005 PDF

Sloane, A.J., Raso, V., Dimitrov, D.S., Xiao, X., Deo, S., Muljadi, N., Restuccia, D., Turville, S., Kearney, C., Broder, C.C., Zoellner, H., Cunningham, A.L., Bendall, L., Lynch, G.W. Marked structural and functional heterogeneity in CXCR4: Separation of HIV-1 and SDF-1alpha responses. Immunol. Cell. Biol. 83(2): 129-143, 2005 PDF

2004

Kasabov, N.K., Chan, Z.S.H., Jain, V., Sidorov, I., Dimitrov, D.S. Gene regulatory network discovery from time-series gene expression data - a computational intelligence approach. Lecture Notes in Computer Science 3316: 1344-1354, 2004 PDF

Huentelman, M.J., Zubcevic, J., Hernandez Prada, J.A., Xiao, X., Dimitrov, D.S., Raizada, M.K., Ostrov, D.A. Structure-based discovery of a novel angiotensin-converting enzyme 2 inhibitor. Hypertension 44: 903-906, 2004 PDF

Xiao, X., Dimitrov, D.S. Cell biology of virus entry: a review of the 4th International Frederick Meeting. Mol. Membr. Biol. 21(5): 281-287, 2004

Xiao, X., Dimitrov, D.S. The SARS-CoV S glycoprotein. Cell. Mol. Life Sci. 61(19-20): 2428-2430, 2004

Xiao, X., Feng, Y., Chakraborti, S., Dimitrov, D.S. Oligomerization of the SARS-CoV S glycoprotein: dimerization of the N-terminus and trimerization of the ectodomain. Biochem. Biophys. Res. Commun. 322(1): 93-99, 2004 PDF

Zhang, M.-Y., Xiao, X., Sidorov, I.A., Choudhry, V., Cham, F., Zhang, P.F., Bouma, P., Zwick, M., Choudhary, A., Montefiori, D.C., Broder, C.C., Burton, D.R., Quinnan, G.V., Jr., Dimitrov, D.S. Identification and characterization of a new cross-reactive human immunodefficiency virus Type 1 neutralizing human monoclonal antibody J. Virol. 78(17): 9233-9242, 2004 PDF

Huang, C.C., Venturi, M., Majeed, S., Moore, M.J., Phogat, S., Zhang, M.Y., Dimitrov, D.S., Hendrickson, W.A., Robinson, J., Sodroski, J., Wyatt, R., Choe, H., Farzan, M., Kwong, P.D. Structural basis of tyrosine sulfation and VH-gene usage in antibodies that recognize the HIV type 1 coreceptor-binding site on gp120. Proc. Natl. Acad. Sci. U.S.A. 101(9): 2706-2711, 2004 PDF

Darbha, R., Phogat, S., Labrijn, A.F., Shu, Y., Gu, Y., Andrykovitch, M., Zhang, M.Y., Pantophlet, R., Martin, L., Vita, C., Burton, D.R., Dimitrov, D.S., Ji, X. Crystal structure of the broadly cross-reactive HIV-1-neutralizing Fab X5 and fine mapping of its epitope. Biochemistry 43(6): 1410-1417, 2004 PDF

Zhang, M.-Y., Shu, Y., Sidorov, I., Dimitrov, D.S. Identification of a novel CD4i human monoclonal antibody Fab that neutralizes HIV-1 primary isolates from different clades. Antiviral Research 61: 161-164, 2004 PDF

Moulard, M., Zhang, M.-Y., Dimitrov, D.S. Novel HIV neutralizing antibodies selected from phage display libraries. In: Antibodies Vol. 2 (Subramanian, G., ed), Kluwer, New York, 2004, pp.105-117 PDF

Dimitrov, D.S. Virus entry: molecular mechanisms and biomedical applications. Nature Reviews, Microbiology 2: 109-122, 2004 PDF

Prabakaran, P., Xiao, X., Dimitrov, D.S. A model of the ACE2 structure and function as a SARS-CoV receptor. Biochem. Biophys. Res. Commun. 314: 235-241, 2004 PDF

Zhang, M.-Y., Shu, Y., Rudolph, D., Prabakaran, P., Labrijn, A.F., Zwick, M.B., Lal, R.B., Dimitrov, D.S. Improved breadth and potency of an HIV-1-neutralizing human single-chain antibody by random mutagenesis and sequential antigen panning. J. Mol. Biol. 335: 209-219, 2004 PDF

Sidorov, I.A., Gee, D., Dimitrov, D.S. A kinetic model of telomere shortening in infants and adults. J. Theor. Biol., 226(2): 169-175, 2004 PDF

2003

Zhang, M.-Y., Shu, Y., Phogat, S., Xiao, X., Cham, F., Bouma, P., Choudhary, A., Feng, Y.-R., Sanz, I., Rybak, S., Broder, C.C., Quinnan, G.V.Jr., Evans, T., Dimitrov, D.S. Broadly cross-reactive HIV neutralizing human monoclonal antibody Fab selected by sequential antigen panning of a phage display library J. Immunol. Meth. 283: 17-25, 2003 PDF

Dimitrov D.S. The secret life of ACE2 as a receptor for the SARS virus. Cell 115(6): 652-653, 2003 PDF

Xiao, X., Chakraborti, S., Dimitrov, A., Gramatikoff, K., Dimitrov D.S. The SARS-CoV S glycoprotein: expression and functional characterization. Biochem. Biophys. Res. Commun. 312: 1159-1164, 2003 PDF

Xiao, X., Athanasiou, M., Sidorov, I.A., Horikawa, I., Cremona, G., Blair, D., Barret, J.C., Dimitrov, D.S. Role of Ets/Id proteins for telomerase regulation in human cancer cells. Exp. Mol. Pathol., 75(3): 238-247, 2003 PDF

Xiao, X., Phogat, S., Shu, Y., Phogat, A., Chow, Y.H., Wei, O.L., Goldstein, H., Broder, C.C., Dimitrov, D.S. Purified complexes of HIV-1 envelope glycoproteins with CD4 and CCR5(CXCR4): production, characterization and immunogenicity. Vaccine, 21(27-28): 4275-4284, 2003 PDF

Tan, P.K., Downey, T.J., Spitznagel, Jr. E.L. Jr., Xu, P., Fu, D., Dimitrov, D.S., Lempicki, R.A., Raaka, B.M., Cam, M.C. Evaluation of gene expression measurements from commercial microarray platforms. Nucleic Acids Res., 31(19): 5676-5684, 2003 PDF

Labrijn, A.F., Poignard, P., Raja, A., Zwick, M.B., Delgado, K., Franti, M., Binley, J., Vivona, V., Grundner, C., Huang, C.C., Venturi, M., Petropoulos, C.J., Wrin, T., Dimitrov, D.S., Robinson, J., Kwong, P.D., Wyatt, R.T., Sodroski, J., Burton, D.R. Access of antibody molecules to the conserved coreceptor binding site on glycoprotein gp120 is sterically restricted on primary human immunodeficiency virus type 1. J. Virol., 77(19): 10557-10565, 2003 PDF

Phogat, S.K., Dimitrov, D.S. Cell biology of virus entry: a review of selected topics from the 3rd International Frederick meeting. Biochim. Biophys. Acta, 1614(1): 85-8, 2003 PDF

Bouma, P., Leavitt, M., Zhang, P.F., Sidorov, I.A., Dimitrov, D.S., Quinnan, G.V. Jr. Multiple Interactions across the Surface of the gp120 Core Structure Determine the Global Neutralization Resistance Phenotype of Human Immunodeficiency Virus Type 1. J. Virol., 77(14): 8061-8071, 2003 PDF

Staudinger, R., Phogat, S.K., Xiao, X., Wang, X., Dimitrov, D.S., Zolla-Pazner, S. Evidence for CD4-enchanced Signaling through the Chemokine Receptor CCR5. J. Biol. Chem., 278(12): 10389-10392, 2003 PDF

Leavitt, M., Park, E.J., Sidorov, I.A., Dimitrov, D.S., Quinnan, G.V. Jr. Concordant modulation of neutralization resistance and high infectivity of the primary HIV-1 MN strain and definition of a potential gp41 binding site in gp120. J. Virol., 77(1): 560-570, 2003 PDF

Sidorov, I.A., Hirsch, K.S., Harley, C.B., Dimitrov, D.S. Cancer treatment by telomerase inhibitors: predictions by a kinetic model. Math. Biosci., 181: 209-221, 2003 PDF

2002

Moulard, M., Phogat, S., Shu, Y., Labrijn, A.F., Xiao, X., Binley, J.M., Zhang, M.-Y., Sidorov, I.A., Broder, C.C., Robinson, J., Parren, P.W.H.I., Burton, D.R., Dimitrov, D.S. Broadly cross-reactive HIV-1 neutralizing human monoclonal Fab selected for binding to gp120-CD4-CCR5 complexes. Proc. Natl. Acad. Sci. U.S.A., 99(10): 6913-6918, 2002 PDF

Chow, Y.-H., Wei, O.L., Phogat, S., Sidorov, I.A., Fouts, T.R., Broder, C.C., Dimitrov, D.S. Conserved structures exposed in HIV-1 envelope glycoproteins stabilized by flexible linkers as potent entry inhibitors and potential immunogens. Biochemistry, 41(22): 6256-6262, 2002 PDF

Golding, H., Zaitseva, M., de Rosny, E., King, L.R., Manischewitz, J., Sidorov, I.A., Gorny, M.K., Zolla-Pazner, S., Dimitrov, D.S., Weiss, C.D. Dissection of HIV-1 entry with neutralizing antibodies to gp41 fusion intermediates. J. Virology, 76:6780-6790, 2002 PDF

Xiao, X., Phogat, S., Sidorov, I.A., Yang, J., Horikawa, I., Prieto, D., Adelesberger, J., Lempicki, R., Barrett, J.C., and Dimitrov, D.S. Identification and characterization of rapidly dividing U937 clones with differential telomerase activity and gene expression profiles: Role of c-Myc/Mad1 and Id/Ets proteins. Leukemia, 16(9):1877-1880, 2002 PDF

Biragyn, A., Belyakov, I.M., Chow, Y.H., Dimitrov, D.S., Berzofsky, J.A., Kwak, L.W. DNA vaccines encoding HIV-1 gp120 fusions with proinflammatory chemo-attractants induce systemic and mucosal immune responses. Blood, 100(4):1153-1159, 2002 PDF

Cristillo, A.D., Xiao, X., Campbell-Malone, R., Dimitrov, D.S., Bierer, B.E. Differences between CEM and human peripheral blood T lymphocytes in cAMP-dependent HIV viral fusion and CXCR4 expression. Exp. Mol. Path., 73(1):9-18, 2002 PDF

Peng, B., Voltan, R., Lim, L., Edghill-Smith, Y., Phogat, S., Dimitrov, D.S., Arora, K., Leno, M., Than, S., Woodward, R., Markham, P.D., Cranage, M., Robert-Guroff, M. Rhesus macaque resistance to mucosal SIV infection is associated with post-entry block in viral replication. J. Virology, 76(12): 6016-6026, 2002 PDF

Cristillo, A.D., Highbarger, H.C., Dewar, R.L., Dimitrov, D.S., Golding, H., Bierer, B.E. Up-regulation of HIV coreceptor CXCR4 expression in human T lymphocytes is mediated in part by a cAMP-responsive element. FASEB J., 16(3): 354-364, 2002 PDF

Sidorov, I.A., Hirsch, K.S., Harley, C.B., Dimitrov, D.S. Cancer cell dynamics in presence of telomerase inhibitors: analysis of in vitro data. J. Theor. Biol., 219: 225-233, 2002 PDF

Sidorov, I.A., Hosack, D.A., Gee, D., Yang, J., Cam, M.C., Lempicki, R.A., Dimitrov, D.S. Oligonucleotide microarray data distribution and normalization. Information Sciences 146(1-4): 67-73, 2002 PDF

2001

Kovacs, J.A., Lempicki, R.A., Sidorov, I.A., Adelsberger, J.W., Herpin, B., Metcalf, J.A., Polis, M.A., Davey, R.T., Tavel, J., Falloon, J., Stevens, R., Lambert, L., Dewar, R., Schwartzentruber, D.J., Anver, M.R., Baseler, M.W., Masur, H., Dimitrov, D.S., Lane H.C. Identification of dynamically distinct subpopulations of T lymphocytes that are differentially affected by HIV. J. Exp. Med., 194(12): 1731-1741, 2001 PDF

Dimitrov, D.S., Sidorov, I.A., Endo, Y., Igarashi, T., Lempicki, R.A., Kovacs, J.A., Davey, R.T., Lifson, J., Martin, M.A., and Lane, H.C. Dynamic models of virus/cell turnover in HIV infections. Proc. Atl. Symp. Comput. Biol. Genome Information Systems and Technology (CBGIST 2001), Eds. Wu, C.H., Wang, P.P, Wang, J.T.L., Durham, p. 200-204, 2001 PDF

Polis, M.A., Sidorov, I.A., Yoder, C., Jankelevich, S., Metcalf, J., Mueller, B.U., Dimitrov, M.A., Pizzo, P., Yarchoan, R., Dimitrov, D.S. Correlation between reduction in plasma HIV-1 RNA concentration 1 week after start of antiretroviral treatment and longer-term efficacy. Lancet, 358: 1760-1765, 2001 PDF

Dimitrov, A.S., Xiao, X., Dimitrov, D.S., Blumenthal, R. Early intermediates in HIV-1 envelope glycoprotein-mediated fusion triggered by CD4 and coreceptor complexes. J. Biol. Chem. 276(32): 30335-30341, 2001 PDF

2000

Lempicki, R.A., Kovacs, J.A., Baseler, M.W., Adelsberger, J.W., Metcalf, J.A., Stevens, R.A., Lambert, L.A., Polis, M.A., Alvord, W.G., Dimitrov, D.S., and Lane, H.C. Impact of therapy on the kinetics of CD4+ and CD8+ T cell turnover in HIV-infected patients receiving highly active antiretroviral therapy or interleukin-2. Proc. Natl. Acad. Sci. U.S.A., 97: 13778-83, 2000 PDF

Shen, W., Li, B., Wetzel, M.A., Rogers, T.J., Henderson, E.E., Su, S.B., Gong, W., Le, Y., Sargent, R., Dimitrov, D.S., Oppenheim, J.J., and Wang, J.M. Down-regulation of the chemokine receptor CCR5 by activation of chemotactic formyl peptide receptor in human monocytes. Blood, 96: 2887-94, 2000 PDF

Xiao, X., Norwood, D., Feng, Y-R., Moriuchi, M., Jones-Trower, A., Moriuchi, H., Border, C.C., and Dimitrov, D.S. Inefficient formation of a complex among CXCR4, CD4 and gp120 in U937 clones resistant to X4 gp120-gp41-mediated fusion. Exp. Mol. Pathol. 68(3): 139-146, 2000 PDF

Xiao, X., Kinter, A., Broder, C.C., and Dimitrov, D.S. Interactions of CCR5 and CXCR4 and gp120 in human blood monocyte-derived dentritic cells. Exp. Mol. Pathol. 68(3): 133-138, 2000 PDF

Hug, P., Han-Min, J.L., Korte, T., Xiao, X., Dimitrov, D., Ji, M. W., Puri, A., and Blumenthal, R. Glycosphingolipids promote entry of a broad range of human immunodeficiency virus type 1 isolates into cell lines expressing CD4, CXCR4 and/or CCR5. J. Virol. 74(14): 6377-6385, 2000 PDF

Endo, Y., Igarashi, T., Nishimura, Y., Buckler, C., Buckler-White, A., Plishka, R., Dimitrov, D.S., and Martin, M.A. The short and long term clinical outcomes in rhesus monkeys inoculated with a highly pathogenic chimeric Simian/Human immunodeficiency virus. J. Virology, 74(15): 6935-6945, 2000 PDF

Chabot, D.J., Chen, H., Dimitrov, D.S., and Broder, C.C. N-linked glycosylation of CXCR4 masks coreceptor function for CCR5-dependent human immunodeficiency virus type 1 isolates. J. Virol. 74(9): 4404-4413, 2000 PDF

1999

Davey, R.T., Bhat, N., Yoder, C., Chun, T., Metcalf, J.A., Dewar, R., Natarajan, V., Lempicki, R.A., Adelsberger, J.W., Miller, K.D., Kovacs, J.A., Polis, M.A., Walker, R.E., Falloon, J., Masur, H., Gee, D., Baseler, M., Dimitrov, D.S., Fauci, A.S., and Lane, H.C. The NoHRT Trial: HIV-1 and T cell dynamics following interruption of HAART in patients with a history of sustained viral suppression. Proc. Natl. Acad. Sci. U.S.A., 96(26): 15109-15114, 1999 PDF

Feng, Y., Biggar, R.J., Gee, D., Norwood, D., Zeichner, S.L., Dimitrov, D.S. Long-term telomere dynamics: modest increase of cell turnover in HIV-infected individuals followed for up to 14 years. Pathobiology 67(1): 34-8, 1999

Shibata, R., Feng, Y., Gee, D., Norwood, D., Xiao, X., Zeichner, S. L., Martin, M., Dimitrov, D.S. Telomere dynamics in monkeys: increased cell turnover in macaques infected with chimeric simian-human immunodeficiency viruses. J. Medical Primatology 28(1): 1-10, 1999

Zeichner, S.L., Palumbo, P., Feng, Y., Xiao, X., Gee, D., Sleasman, J., Goodenow, M., Biggar, R., Dimitrov, D.S. Rapid shortening of telomeres in children. Blood, 93(9): 2824-30, 1999 PDF

Igarashi, T., Brown, C., Azadegan, A., Haigwood, N., Dimitrov, D., Martin, M.A., Shibata, R. Human immunodeficiency virus type 1 neutralizing antibodies accelerate clearance of cell-free virions from blood plasma. Nature Medicine, 5(2): 211-6, 1999 PDF

Dimitrov, D.S., Norwood, D., Stantchev, T.S., Feng, Y., Xiao, X., Broder, C.C. A mechanism of resistance to HIV-1 entry: inefficient interactions of CXCR4 with CD4 and gp120 in macrophages. Virology, 259(1): 1-6, 1999 PDF

Grossman, Z., Herberman, R., Dimitrov, D.S. T cell turnover in SIV infection. Science, 284: 555a-b, 1999 PDF

Grossman, Z., Polis, M., Feinberg, M.B., Grossman, Z., Levi, I., Jankelevich, S., Yarchoan, R., Boon, J., de Wolf, F., Lange, J.M.A., Goudsmit, J., Dimitrov, D.S., and Paul, W.E. Ongoing HIV-1 dissemination under HAART. Nature Medicine, 5(10): 1099-104, 1999 PDF

Xiao, X., Wu, L., Stantchev, T.S., Feng, Y-R., Ugolini, S., Chen, H., Shen, Z., Riley, J. L., Broder, C. C., Sattentau, Q. J., and Dimitrov, D. Constitutive cell surface association between CD4 and CCR5. Proc. Natl. Acad. Sci. U.S.A., 96: 7496-7501, 1999 PDF

Golding, H., Gershoni, J. M., Ouyang, J., Zaitseva, M., Broder, C.C., Dimitrov, D.S., Lapham, C. Increased association of gp120-CD4 with HIV-1 co-receptors in the presence of complex-enhanced anti-CD4 monoclonal antibodies. AIDS Res. Hum. Retroviruses 15: 149-159, 1999

1998

Dimitrov, D.S., Xiao, X., Chabot, D., Broder, C.C. HIV coreceptors. J. Membr. Biol., 166: 75-90, 1998 PDF

Norwood, D., Dimitrov, D. A sensitive method for measuring telomere lengths by quantifying telomeric DNA content of whole cells. Biotechniques 25: 1040-1045, 1998

Mueller, B.U., Zeichner, S.L., Kuznetsov, V.A., Heath-Chiozzi, M., Pizzo, P.A., Dimitrov, D.S. Individual prognoses of long-term responses to antiretroviral treatment based on virological, immunological and pharmacological parameters measured during the first week under therapy. AIDS 12: F191-F196, 1998

Grossman, Z., Feinber, M., Kuznetsov, V., Dimitrov, D.S., Paul, W.E. HIV infection: How effective is drug treatment? Immunol. Today 19: 528-532, 1998 PDF

Feng, Y-R., Norwood, D., Shibata, R., Gee, D., Xiao, X., Martin, M., Zeichner, S.L., Dimitrov, D.S. Telomere dynamics in HIV-1 infected and uninfected chimpanzees measured by an improved method based on high-resolution two-dimensional calibration of DNA sizes. J. Med. Primatol. 27: 258-265, 1998

1997

Mackall, C.L., Fleisher, T.A., Brown, M.R., Andrich, M.P., Chen, C.C., Feuerstein, I.M., Magrath, I.T., Wexler, L.H., Dimitrov, D.S., and Gress, R.E. Distinctive patterns of CD8+ and CD4+ regeneration result in prolonged T cell subset imbalance in cancer patients after intensive chemotherapy. Blood, 89: 3700-3707, 1997 PDF

Lowy, R.J. and Dimitrov, D.S. Characterization of influenza virus-induced death of J774.1 macrophages. Exp. Cell Res. 234: 249-258, 1997

Lee, S., Peden, K., Dimitrov, D.S., Broder, C.C., Manischewitz, J., Denisova, G., Gershoni, J.M., Golding, H. Enhancement of HIV-1 envelope-mediated fusion by a CD4-gp120 complex-specific monoclonal antibody. J. Virol. 71: 6037-6043, 1997

1996

Zeichner, S.L., Mueller, B.U., Pizzo, P.A., and Dimitrov, D.S. Kinetics of HIV-1 RNA concentration changes in pediatric patients. Pathobiology 64: 289-294, 1996

Spouge, J.L., Shrager, R.I., and Dimitrov, D.S. HIV-1 infection kinetics in tissue cultures. Bulletin of Mathematical Biosciences 138: 1-22, 1996

Lapham, C.K., Ouyang, J., Chandrasekhar, B., Nguyen, N.Y., Dimitrov, D.S., Golding, H. Evidence for cell-surface association between fusin and the CD4-gp120 complex in human cell lines. Science 274: 602-605, 1996

Dimitrov, D.S. and Apostolova, M.A. The limit of PCR amplification. J. Theor. Biol. 178: 425-426, 1996 PDF

Dimitrov, D. S.: Fusin - a place for HIV-1 and T4 cells to meet. The identification of the long sought coreceptor mediating HIV-1 entry raises new hopes for AIDS prevention and treatment. Nature Med. 2: 640-641, 1996.

1995

Golding, H., Dimitrov, D. S., Manischewitz, J., Broder, C. C., Robinson, J., Fabian, S., Littman, D. R., and Lapham, C. K.: PMA-induced downmodulation of tailless CD4 receptors requires prior binding of gp120 and suggests a role for accessory molecules. J. Virol. 169: 4267-4273, 1995.

Dimitrov, D. S. and Martin, M. A.: HIV results in the frame - CD4+ cell turnover. Nature 375: 194-195, 1995.

Burkly, L., Mulrey, N., Blumenthal, R., and Dimitrov, D. S.: Synergistic inhibition of HIV-1 envelope glycoprotein-mediated cell fusion and infection by an antibody to CD4 domain 2 in combination with anti-gp120 antibodies. J. Virol. 69: 4267-4273, 1995.

1994

Vicenzi, E., Dimitrov, D. S., Engelman, A., Migone, T-S., Purcell, D. F. J., Englund, G., and Martin, M. A.: An integration defective U5 deletion mutant of HIV-1 reverts by eliminating additional LTR sequences. J. Virol. 68: 7879-7890, 1994.

Golding, H., Manischewitz, J., Vujcic, L., Blumenthal, R., and Dimitrov, D. S.: The phorbol ester PMA inhibits HIV-1 envelope-mediated fusion by modulating accessor component(s) in CD4 expressing cells. J. Virol. 68: 1962-1969, 1994.

Elson, H. F., Dimitrov, D. S., and Blumenthal, R.: A trans-dominant mutation in human immunodeficiency virus type 1 (HIV-1) envelope glycoprotein gp41 inhibits membrane fusion when expressed in target cells. Mol. Membr. Biol. 11: 165-169, 1994.

Dimitrov, D. S. and Blumenthal, R.: Photoinactivation and kinetics of membrane fusion mediated by the HIV-1 envelope glycoprotein. J. Virol. 68: 1956-1961, 1994.

1993

Puri, A., Krumbiegel, M., Dimitrov, D. S., and Blumenthal, R.: A new approach to measure fusion activity of cloned viral envelope proteins: Fluorescence dequenching of octadecylrhodamine labeled plasma membrane vesicles fusing with cells expressing vesicular stomatitis virus glycoprotein. Virology 195: 855-858, 1993.

Golding, H., Dimitrov, D. S., Blackburn, R., Manischewitz, J., Blumenthal, R., and Golding, B.: Fusion of human B cell lines with HIV-1 envelope-expressing T cells is enhanced by antigen-specific immunoglobulin receptors: A possible mechanism for elimination of gp120-specific B cells in vivo. J. Immunol. 150: 2506-2516, 1993.

Golding, H., Blumenthal, R., Manischewitz, J., Littman, D. R., and Dimitrov, D. S.: Cell fusion mediated by interaction of a hybrid CD4.CD8 molecule with the HIV-1 envelope glycoprotein does occur after a long lag time. J. Virol. 67: 6469-6475, 1993.

Dimitrov, D. S., Willey, R. L., Sato, H., Chang, L-J., Blumenthal, R., and Martin, M. A.: Quantitation of HIV-1 infection kinetics. J. Virol. 67: 2182-2190, 1993.

Dimitrov, D. S., Broder, C. C., Berger, E. A., and Blumenthal, R.: Calcium ions are required for cell fusion mediated by the CD4-HIV-1 envelope glycoprotein interaction. J. Virol. 67: 1647-1652, 1993.

Dimitrov, D. S.: Kinetic mechanisms of membrane fusion mediated by electric fields. Bioelectrochemisty and Bioenergetics 32: 99-124, 1993.

Broder, C. C., Dimitrov, D. S., Blumenthal, R., and Berger, E. A.: The block to HIV-1 envelope glycoprotein-mediated membrane fusion in animal cells expressing human CD4 can be overcome by a human cell component(s). Virology 193: 483-491, 1993.

1992

Sato, H., Ornstein, J., Dimitrov, D. S., and Martin, M.: Cell-to-cell spread of HIV-1 occurs within minutes and may not involve participation of virus particles. Virology 186: 712-724, 1992.

Puri, A., Dimitrov, D. S., and Blumenthal, R.: Interactions of CD4+ plasma membrane vesicles with HIV-1 and HIV-1 envelope expressing cells. J. AIDS 5: 915-920, 1992.

Krumbiegel, M., Dimitrov, D. S., Puri, A., and Blumenthal, R.: Dextran sulfate inhibits fusion of influenza virus and cells expressing influenza hemagglutinin with red blood cells. Biochim. Biophys. Acta 1110: 158-164, 1992.

Golding, H., Dimitrov, D. S., and Blumenthal, R.: LFA-1 adhesion molecules are not involved in early stages of HIV-1-env-mediated cell membrane fusion. AIDS Res. Hum. Retroviruses 8: 1607-1612, 1992.

Franzoso, G., Dimitrov, D. S., Blumenthal, R., Barlie, M. F., and Rottem, S.: Fusion of Mycoplasma fermentas strain incognitus with T-lymphocytes. FEBS Lett. 303: 251-254, 1992.

Dimitrov, D. S., Willey, R., Martin, M., and Blumenthal, R.: Kinetics of HIV-1 interactions with sCD4 and CD4+ cells. Implications for inhibition of virus infection and initial steps of virus entry into cells. Virology 187: 398-406, 1992.

Dimitrov, D. S., Hillman, K., Manischewitz, J., Blumenthal, R., and Golding, H.: Kinetics of interaction of soluble CD4 interactions with cells expressing HIV-1 envelope and inhibition of syncytia formation: Implications for mechanisms of cell fusion and therapy of AIDS. AIDS 6: 249-256, 1992.

Dimitrov, D. S., Hillman, K., Manischewitz, J., Blumenthal, R., and Golding, H.: Kinetics of binding of sCD4 to cells expressing HIV-1 envelope glycoprotein. J. Virol. 66: 132-138, 1992.

1991

Zhelev, D. V., Kuzmin, P., and Dimitrov, D. S.: Mutual dielectrophoresis of cells. Bioelectrochemistry and Bioenergetics 26: 193-203, 1991.

Dimitrov, D. S., Golding, H., and Blumenthal, R.: Initial steps in HIV-1 envelope glycoprotein mediated cell fusion monitored by a new assay based on redistribution of fluorescence markers. AIDS Res. Hum. Retroviruses 7: 799-805, 1991.

1990

Dimitrov, D. S. and Sowers, A. E.: Membrane electroporation - fast molecular exchange by electroosmosis. Biochim. Biophys. Acta 1022: 381-392, 1990.

Dimitrov, D. S. and Sowers, A. E.: A delay in membrane fusion: Lag times observed by fluorescence microscopy of individual fusion events induced by an electric field pulse. Biochemistry 29: 8337-8344, 1990.

Dimitrov, D. S., Apostolova, M., and Sowers, A. E.: Approach, deformation and contact of membranes induced by electric fields. Biochim. Biophys. Acta 1023: 389-397, 1990.

1989

Zhelev, D. V. and Dimitrov, D. S.: Electrofusion of pea protoplasts in polyethylene glycol solutions. Studia Biophysica 130: 165-168, 1989.

Tsoneva, I., Doinov, P., and Dimitrov, D. S.: Electrofusion of fragile mutants of Saccharommyces cerevisiae. FEMS Microbiol. Lett. 60: 61-66, 1989.

Doinov, P., Stoicheva, N., and Dimitrov, D. S.: Polarizabilities and densities of individual protoplasts: Experimental methods and results. Studia Biophysica 130: 169-172, 1989.

Dimitrov, D. S. and Doinov, P.: Dielectrophoresis, instability and electrofusion in membrane systems. J. Colloid Polymer Sci. 79: 1-5, 1989.

Dimitrov, D. S. and Doinov, P.: Biophysical engineering in biotechnology. Biotechnology and Chemistry 1: 1-9, 1989.

1988

Zhelev, D. V., Dimitrov, D. S., and Tsoneva, I.: Electrical breakdown of protoplasts membranes under different osmotic pressures. Bioelectrochemistry and Bioenergetics 19: 217-225, 1988.

Zhelev, D. V., Dimitrov, D. S., and Doinov, P.: Correlation between physical parameters in electrofusion and electroporation of protoplasts. Bioelectrochemistry and Bioenergetics 20: 155-167, 1988.

Tsoneva, I., Panova, I., Doinov, P., Dimitrov, D. S., and Strahilov, D.: Hybridoma production by electrofusion: Monoclonal antibodies against the Hc antigene of salmonella. Studia Biophysica 125: 31-35, 1988.

Ivanov, I. B. and Dimitrov, D. S.: Thin film drainage. In Ivanov, I. B. (Ed.): Thin Liquid Films. New York, Marcel Dekker, 1988, pp. 379-496.

Dimitrov, D. S. and Zhelev, D.: Fluctuation wave mechanism of membrane electrofusion. Prog. Colloid Polymer Sci. 76: 26-31, 1988.

Dimitrov, D. S. and Angelova, M.: Lipid swelling and liposome formation mediated by electric fields. Bioelectrochemistry and Bioenergetics 19: 323-336, 1988.

Angelova, M. and Dimitrov, D. S.: A mechanism of liposome electroformation. Prog. Colloid Polymer Sci. 76: 67-76, 1988.

1987

Zhelev, D. V., Dimitrov, D. S., and Tsoneva, I.: Electrical breakdown of protoplasts in solutions of different osmolarity. Studia Biophysica 119: 53-56, 1987.

Zhelev, D. V. and Dimitrov, D. S.: Instability to rupture of anisotropic viscoelastic membranes: Dispersion equation and effects of surface elasticity and viscosity. Molecular Crystals and Liquid Crystals 152: 279-291, 1987.

Dimitrov, D. S. and Zhelev, D.: Single cell dielectrophoresis. Dynamic methods. Studia Biophysica 119: 57-60, 1987.

Dimitrov, D. S. and Zhelev, D. V.: Dielectrophoresis of individual cells. Experimental methods and results. Bioelectrochemistry and Bioenergetics 17: 549-557, 1987.

Dimitrov, D. S., Tomov, V., Sharkov, G., and Angelova, M.: Liposome production and protoplast electrofusion expert systems. In Sgurev, V. and Jorrand, P. (Eds.): Proceedings of the Artificial Intelligence and Machine Simulations Association 86. Amsterdam, North Holland, 1987, pp. 219-228.

Dimitrov, D. S. and Angelova, M.: Electric field mediated lipid swelling and electroswelling. Studia Biophysica 119: 61-65, 1987.

Angelova, M. and Dimitrov, D. S.: Swelling of charged lipids and formation of liposomes on electrode surfaces. Molecular Crystals and Liquid Crystals 152: 89-104, 1987.

Angelova, M. and Dimitrov, D. S.: Liposome electroformation. Faraday Discussions of the Chemical Society 81: 303-311 (disc.345-349), 1987.

1986

Weiss, L. and Dimitrov, D.S.: Mechanical aspects of the lungs as cancer cell-killing organs during hematogenous metastasis. J. Theor. Biol. 121: 307-321, 1986.

Tsoneva, I., Zhelev, D. V., and Dimitrov, D. S.: Dielectrophoresis of red blood cells in axisymmetric fields. Cell Biophys. 8: 89-101, 1986.

Stoicheva, N. and Dimitrov, D. S.: Frequency effects in protoplast dielectrophoresis. Electrophoresis 7: 339-341, 1986.

Stoicheva, N. and Dimitrov, D. S.: Dielectrophoresis of single protoplasts: Effects of increased conductivity caused by calcium ions. Studia Biophys. 111: 17-21, 1986.

Stoicheva, N. and Dimitrov, D. S.: Dielectrophoresis of myeloma cells, hybridomas and B lymphocytes. Proc. Bulg. Acad. Sci. 39: 105-107, 1986.

Dimitrov, D. S. and Zhelev, D.: Dynamics and stability of membrane systems. Int. Biotechnol. Lab. 4: 12-20, 1986.

Dimitrov, D. S. and Angelova, M.: Dynamics of swelling and electroswelling of lipids: Theory and experiment. Studia Biophys. 113: 15-20, 1986.

Dimitrov, D. S.: Approach and instability of membranes: Physicochemical mechanisms and applications to adhesion, fusion, dielectrophoresis, electroporation and liposome formation. Proc. 8th School on Biophysics of Membrane Transport. Poland, Mierki, 1986, pp. 51-82.

1985

Zhelev, D. V. and Dimitrov, D. S.: Stability of membrane systems modeled as thin films: Applications to membrane adhesion and fusion. Int. Agrophysics 1(2): 205-217, 1985.

Weiss, L. and Dimitrov, D. S.: Metastasis peculiarities, metastasis inefficiency and mechanical destruction of cancer cells in lung microcirculation. Oncology 23: 1-6, 1985.

Weiss, L., Angelova, M., and Dimitrov, D. S.: The hemodynamic destruction of intravascular cancer cells in relation to myocardial metastasis. Proc. Natl. Acad. Sci. USA. 82: 5737-5741, 1985.

Stoicheva, N., Tsoneva, I., and Dimitrov, D. S.: Protoplast dielectrophoresis in axisymmetric fields. Z. Naturforsch. 40: 735-739, 1985.

Stoicheva, N., Dimitrov, D. S., Tsoneva, I., and Panaiotov, I.: Kinetics of calcium induced fusion of cell-size liposomes with phospholipid monolayers in solutions of different osmolarity. Z. Naturforsch. 40: 92-96, 1985.

Ivanov, I. B., Dimitrov, D. S., Jain, R. K., and Somasundaran , P.: General formulation of the theory of formation and thinning of wetting and foam films with deformable surfaces. Chem. Eng. Sci. 40: 137-150, 1985.

Dimitrov, D. S., Zhelev, D. V., and Jain, R. K.: Stability of viscoelastic membrane systems, modeled as multilayered thin films. J. Theor. Biol. 113: 353-377, 1985.

Dimitrov, D. S. and Zhelev, D.: Dynamics of membrane stability and fusion. Studia Biophys. 110: 105-111, 1985.

Dimitrov, D. S. and Angelova, M.: Surface and electric field effects in preparation of cell-size liposomes. Proc. Biotech 85 (1). Europe, 1985, pp. 655-660.

1984

Weiss, L. and Dimitrov, D. S.: A fluid mechanical analysis of the velocity, adhesion and destruction of cancer cells in capillaries during metastasis. Cell Biophys. 6: 9-22, 1984.

Tsoneva, I., Zhelev, D. V., and Dimitrov, D. S.: Electromagnetic fusion of membranes in cell dielectrophoresis. Proc. 35th Meeting Int. Soc. Electrochem. Berkeley, 1984, pp. 1001-1003.

Stoicheva, N., Tsoneva, I., and Dimitrov, D. S.: Fusion of giant liposomes with monolayers. Proc. Acad. Bulg. Sci. 37: 1107-1110, 1984.

Mutafchieva, R., Panaiotov, I., and Dimitrov, D. S.: Surface pressure hysteresis of mixed lipid/protein monolayers: Applications to the alveolar dynamics. Z. Naturforsch. [C] 39: 965-970, 1984.

Dimitrov, D. S. and Zhelev, D.: Stability of multi-layered thin liquid films: Applications to membrane systems. J. Colloid Interface Sci. 99: 324-334, 1984.

Dimitrov, D. S., Tsoneva, I., Stoicheva, N., and Zhelev, D.: An assay for dielectrophoresis: Applications to electromagnetically induced membrane adhesion and fusion. J. Biol. Phys. 12: 26-30, 1984.

Dimitrov, D. S., Stoicheva, N., and Stefanova, D.: A simple interpolation formula for the rate of approach of particles or cells with tension-controlled shape at arbitrary separations. J. Colloid Interface Sci. 98: 269-271, 1984.

Dimitrov, D. S., Li, J., Angelova, M., and Jain, R.: Surface effects in preparation of cell-size liposomes. FEBS Lett. 176: 398-400, 1984.

Dimitrov, D. S. and Jain, R. K.: Stability of thin viscoelastic films between permeable membranes. J. Colloid Interface Sci. 101: 489-499, 1984.

Dimitrov, D. S., Ivanov, I. B., and Traykov, T. T.: Influence of permeability on the rate of mutual approach of membranes. J. Membr. Sci. 17: 79-87, 1984.

Dimitrov, D. S. and Banarez, R.: MEFES: A membrane fusion expert system. In Squrev, V. (Ed.): Proc. Int. Conf. Artificial Intelligence, Microfische 2. Varna, BAN, 1984.

Dimitrov, D. S.: Electrical breakdown of lipid bilayers and cell membranes - a thin viscoelastic film model. J. Membr. Biol. 78: 53-60, 1984.

Dimitrov, D. S.: Dynamics of longitudinal deformations of monolayers from membrane components. J. Phys. Chem. 59: 458-463, 1984.

1982

Dimitrov, D. S. and Stoilova, S.: A hydrodynamic theory of bilayer membrane formation and some hypotheses about the mechanism of cell adhesion kinetics. Studia Biophys. 90: 103-104, 1982.

Dimitrov, D. S., Georgiev, G., Stoicheva, N.G., and Traykov, T. T.: Dynamics of viscoelastic spherical membranes - the balloon model of the alveolus. J. Theor. Biol. 96: 517-532, 1982.

Dimitrov, D. S.: Instability of thin liquid films between membranes. J. Colloid Polymer Sci. 260: 1137-1144, 1982.

1981

Dimitrov, D. S., Stoicheva, N. G., and Georgiev, G.: A model of the viscoelastic behavior of the lung parenchymal uniaxial deformations. Studia Biophys. 84: 145-146, 1981.

Dimitrov, D. S., Georgiev G., and Dimitrov, A. S.: Non-steady diffusion of gases through monolayers. I. Phenomenological description. Studia Biophys. 85: 133-134, 1981.

Dimitrov, D. S., Dimitrov, A. S., and Georgiev, G.: Non-steady diffusion of gases through monolayers. II. A cluster model. Studia Biophys. 85: 135-136, 1981.

Dimitrov, D. S.: A hydrodynamic theory of the bilayer membrane formation. Biophys. J. 36: 21-25, 1981.

1980

Tanevas S., Dimitrov, D. S., and Panaiotov, I.: Model Investigations of the alveolar surface. II. Influence of the Marangoni effect, surface pressure relaxations and collapse on the surface pressure hysteresis of dipalmitoyllecithin monolayers. In Georgiev, G. (Ed.): Proc. II Int. Lung Lipid Metabolism, Mechanisms of its Regulation and Alveolar Surfactant. Sofia, Publishing House, 1980, pp. 27-31.

Taneva, S., Dimitrov, D. S., and Panaiotov, I.: Hysteretic cycles of the surface pressure of dipalmitoyllecithin monolayers. Ann. Univ. Sofia, Fac. Chem. 74: 73-81, 1980.

Panaiotov, I., Dimitrov, D. S., Taneva, S., Mutafchieva, R., Vassilev, P., and Georgiev G.: Model investigations of the alveolar surface. VI. Dynamic behavior of the alveolar lining layer - Plane surface model. In Georgiev, G. (Ed.): Proc. II Int. Lung Lipid Metabolism, Mechanisms of its Regulation and Alveolar Surfactant. Sofia, Publishing House, 1980, pp. 67-72.

Panaiotov, I., Dimitrov, D. S., and Georgiev, G.: Viscoelastic relaxation in mixed dipalmitoyllecithin - serum albumin monolayers, modelling the lung surface film. Studia Biophys. 78: 95-102, 1980.

Panaiotov, I. and Dimitrov, D. S.: Model Investigations of the alveolar surface. III. Viscoelastic behavior and surface pressure hysteresis of serum albumin monolayers. Proc. II Int. Lung Lipid Metabolism, Mechanisms of its Regulation and Alveolar Surfactant. In Georgiev, G. (Ed.): Sofia, Publishing House, 1980, pp. 48-53.

Mutafchieva, R., Panaiotov, I., Dimitrov, D. S., and Georgiev, G.: Model Investigations of the alveolar surface. V. Equilibrium and dynamic properties of mixed binary monolayers formed by dipalmitoyllecithin, sphingomyelin and serum albumin. In Georgiev, G. (Ed.): Proc. II Int. Lung Lipid Metabolism, Mechanisms of its Regulation and Alveolar Surfactant. Sofia, Publishing House, 1980, pp. 61-66.

Dimitrov, D. S. and Panaiotov, I.: Model Investigations of the alveolar surface. I. Elastic and viscoelastic behavior of dipalmitoyllecithin monolayers at small deformations. In Georgiev, G. (Ed.): Proc. II Int. Lung Lipid Metabolism, Mechanisms of its Regulation and Alveolar Surfactant. Sofia, Publishing House, 1980, pp. 19-26.

Dimitrov, D. S., Georgiev, G., and Valevski, G: Model investigations of the alveolar surface. VII. Dynamic behavior of the alveolar lining layer and the underlying lung tissue - Bubble model. In Georgiev, G. (Ed.): Proc. II Int. Lung Lipid Metabolism, Mechanisms of its Regulation and Alveolar Surfactant. Sofia, Publishing House, 1980, pp. 73-80.

Dimitrov, D. S. and Georciiev, G.: Kinetics of adsorption (or desorption) induced density change of a monolayer subjected to small deformations. Studia Biophys. 78: 177-187, 1980.

1979

Panaiotov, I., Dimitrov, D. S., and Ter-Minassian-Saraga, L.: Dynamics of insoluble monolayers. II. Viscoelastic behavior and Marangoni effect for mixed protein phospholipid films. J. Colloid Interface Sci. 72: 49-53, 1979.

Panaiotov, I., Dimitrov, D. S., and Ivanova, M.: Influence of bulk-to-surface diffusion interchange on dynamic surface tension excess at uniformly compressed interface. J. Colloid Interface Sci. 69: 318-325, 1979.

Ivanov, I. B., Dimitrov, D. S., and Radoev, B. P.: The general equation of the hydrodynamics of thin liquid films and their application in calculation of the rate of thinning of thin films with non-deformable surfaces. Colloid Zh. 41: 36-41, 1979.

Dimitrov, D. S., Valevski, G., and Georgiev, G.: Equilibrium and stability of the alveolar lining layer: A surface physical chemistry viewpoint. II. Hydrodynamic effects. Studia Biophys. 77: 221-226, 1979.

Dimitrov, D. S., Georgiev, G., and Valevski, G.: Mechanical equilibrium and stability of elastic spherical membranes - the balloon model of the alveolus. Studia Biophys. 77: 201-202, 1979.

Dimitrov, D. S., Georgiev, G., and Valevski, G.: Equilibrium and stability of the alveolar lining layer: A surface physical chemistry viewpoint. I. Thermodynamic treatment. Studia Biophys. 77: 121-132, 1979.

1978

Panaiotov, I., Dimitrov, D. S., and Ter-Minassian-Saraga, L.: Propagation of longitudinal deformations along soluble and insoluble monolayers. Ann. Univ. Sofia, Fac. Chem. 72(l): 81-94, 1978.

Ivanov, I. B., Dimitrov, D. S., and Radoev, B. P.: Hydrodynamics of thin liquid films. Rate of expansion of the perimeter of the three-phase contact line. J. Colloid Interface Sci. 63: 166-168, 1978.

Dimitrov, D. S., Panaiotov, I., Richmond, P., and Ter-Minassian-Saraga, L.: Dynamics of insoluble monolayers. I. Dilational or elastic modulus, friction coefficient and Marangoni effect for dipalmitoyllecithin monolayers. J. Colloid Interface Sci. 65: 483-494, 1978.

Dimitrov, D. S., Panaiotov, I., Ivanova, T.S., and Georgiev, G.: Surface pressure relaxation of dipalmitoyllecithin monolayers. Ann. Univ. Sofia, Fac. Chem. 72(l): 119-130, 1978.

Dimitrov, D. S., and Ivanov, I. B.: Hydrodynamics of thin liquid films. On the rate of thinning of microscopic films with deformable interfaces and validity of the Reynolds law. J. Colloid Interface Sci. 64: 97-106, 1978.

1977

Panaiotov, I., Dimitrov, D. S., Ivanova, M., and Taneva S.: Longitudinal deformations of binary mixtures of soluble and insoluble adsorption layers. Ann. Univ. Sofia, Fac. Chem. 71(2): 27-40, 1977.

Panaiotov, I., Dimitrov, D. S., and Ivanova, M.: Investigation of the dynamic surface pressure of soluble adsorption layers. Ann. Univ Sofia, Fac. Chem. 71(l): 89-100, 1977.

Dimitrov, D. S.: The critical radius of disengagement of a small bubble from a rigid plane. Proc. Bulg. Acad. Sci. 30: 269-270, 1977.

1976

Radoev, B. P. and Dimitrov, D. S.: Hydrodynamics of foam films stabilized by surfactants of low surface activity. Proc. 7th Int. Congress Surface Active Subst. Moscow, Nauka, 1976, pp. 473-479.

Dimitrov, D. S. and Radoev, B. P.: Hydrodynamics of foam films in absence of surfactants Proc. Bulg. Acad. Sci. 29: 1649-1651, 1976.

Dimitrov, D. S. and Panaiotov, I.: Hydrodynamic interaction between an insoluble elastic monolayer and a liquid support in Langmuir trough. Ann. Univ. Sofia, Fac. Chem. 70(l): 103-114, 1976.

Dimitrov, D. S. and Panaiotov, I.: A theoretical investigation of the dynamic surface pressure in the case of longitudinal deformations of viscoelastic monolayers. Ann. Univ. Sofia, Fac. Chem. 70(l): 115-122, 1976.

Dimitrov, D. S.: Deformation of a draining film between a rigid sphere and a gas-liquid interface. Proc. Bulg. Acad. Sci. 29: 1791-1793, 1976.

1975

Dimitrov, D. S. and Radoev, B. P.: Hydrodynamics of foam films in absence of surfactants. Ann. Univ. Sofia, Fac. Chem. 69(l): 33-44, 1975.

Dimitrov, D. S. and Ivanov, I. B.: Mass transport in thin liquid films. Ann. Univ. Sofia, Fac. Chem. 69(2): 73-80, 1975.

Dimitrov, D. S. and Ivanov, I. B.: Hydrodynamics of thin liquid films. Rate of thinning of microscopic films with deformable surfaces and validity of the Reynolds law. Ann. Univ. Sofia, Fac. Chem. 69(l): 83-94, 1975.

Dimitrov, D. S. and Ivanov, I. B.: Hydrodynamics of thin films from noematic liquid crystals. Proc. Bulg. Acad. Sci. 28: 1513-1515, 1975.

Dimitrov, D. S. and Ivanov, I. B.: Hydrodynamics of thin films from noematic liquid crystals. Ann. Univ. Sofia, Fac. Chem. 69(1): 65-82, 1975.

Dimitrov, D. S. and Ivanov, I. B.: Dynamic elasticity of pulsating gas bubble. Ann. Univ. Sofia, Fac. Chem. 69(l): 143-151, 1975.

1974

Radoev, B. P., Dimitrov, D. S., and Ivanov, I. B.: Hydrodynamics of thin liquid films. Effects of surfactants on the rate of thinning. J. Colloid Polymer Sci. 252: 50-55, 1974.

Ivanov, I. B. and Dimitrov, D. S.: Hydrodynamics of thin liquid films. Effect of surface viscosity on thinning and rupture of foam films. J. Colloid Polymer Sci. 252: 982-990, 1974.

1973

Ivanov, I. B., Dimitrov, D. S., and Radoev, B. P.: Hydrodynamics of thin liquid films. The rate of expansion of the perimeter of the three-phase contact line. Ann. Univ. Sofia, Fac. Chem. 67: 377-387, 1973.

1972

Radoev, B. P., Dimitrov, D. S., and Ivanov, I. B.: Hydrodynamics of thin liquid films. Influence of the surfactants on the rate of thinning. Ann. Univ. Sofia, Fac. Chem. 66: 87-98, 1972.

Ivanov, I. B. and Dimitrov, D. S.: Hydrodynamics of thin liquid films. Influence of surface viscosity on the thinning and rupture of foam films. Ann. Univ. Sofia, Fac. Chem. 66: 655-672, 1972.

 

REVIEW IN JOURNALS

Dimitrov, D.S. and Jain, R. K.: Membrane stability. Biochem. Biophys. Acta, Reviews on Biomembranes 779: 437-468, 1984.

Dimitrov, D.S.: HIV-1 infection of cells and AIDS progression. Biomed. Rev. 2: 1-8, 1993.

Broder, C.C. and Dimitrov, D. S.: HIV and the 7-transmembrane domain receptors. Pathobiology 64: 171-179, 1996.

Dimitrov, D. A.: How do viruses enter cells? The HIV coreceptors teach us a lesson of complexity. Cell 91: 1-10, 1997.

Dimitrov, D.S., Xiao, X., Chabot, D., and Broder, C.C.: HIV coreceptors. J. Membr. Biol. 166: 75-90, 1998.

Dimitrov, D.S.: Cell biology of virus entry. Cell 101(7): 697-702, 2000.

 

BOOK CHAPTERS

Dimitrov, D.S., Sidorov, I.A., and Kasabov, N. Computational Biology. In Rieth, M. and Schommers, W. (Eds.): Handbook of Theoretical and Computational Nanotechnology. Stevenson Ranch, CA, American Scientific Publishers, 2006 (in press) PDF

Ivanov, I.B., Radoev, B.P., Traykov, T.T., Dimitrov, D.S., Manev, E.D., and Vassilieff, C.S.: Hydrodynamics of foam and emulsion films. In Wolfram, E. (Ed.): Proc. Int. Conf. Colloid Surface Sci. (1). Akademia Kiado, Budapest, 1975, pp. 583-589.

Dimitrov, D. S.: Dynamic interactions between approaching surfaces of biological interest. In Davison, S. G. (Ed.): Progress in Surface Sci. (14). New York, Pergamon Press, 1983, pp. 295-424

Dimitrov, D. S. and Georgiev, G.: Physicochemical properties of monolayers, modelling the alveolar lining layer of the alveolocapillary membrane. In Berezovski, V. A. (Ed.): Lung Surfactants in Normal and Pathological Conditions. Kiev, Naukova Dumka, 1983, pp. 29-38.

Sharkov, G. and Dimitrov, D. S.: Expert systems in membrane biophysics and engineering - knowledge representation and reasoning. In Plander, I. (Ed.): Artificial Intelligence and Information-Control Systems of Robots-87. Amsterdam, North-Holland, 1987, pp. 455-459.

Sharkov, G. and Dimitrov, D. S.: Knowledge based systems in biophysics: Applications to research in neurobiology of aging and medicine. In Oshea, T. and Sgurev, V. (Eds.): Artificial Intelligence III. Amsterdam, North Holland, 1988, pp. 397-404.

Sharkov, G. and Dimitrov, D. S.: Knowledge representation and reasoning in expert systems for biophysics. In Ras, Z. W. and Saiutta, L. (Eds.): Methodologies for Intelligent Systems III. Amsterdam, North Holland, 1989, pp. 150-159.

Blumenthal, R., Puri, A., and Dimitrov, D. S.: Initial steps of enveloped virus entry into animal cells. In Verna, R. and Nishizuka, Y. (Eds.): Biotechnology of Cell Regulation. New York, Raven Press, 1991, pp. 115-133.

Dimitrov, D. S. and Blumenthal, R.: Kinetics of intermembrane interactions leading to fusion. In Ohki, S. (Ed.): Cell and Model Membrane Interactions. New York, Plenum Press, 1991, pp. 229-247.

Dimitrov, D. S.: Membrane fusion kinetics. In Chang, D. C., Chassy, B. M., Saunders, J. A., and Sowers, A. E. (Eds.): Guide to Electroporation and Electrofusion. Orlando, Academic Press, 1992, pp. 155-166.

Blumenthal, R., Pak, C. C., Krumbiegel, M., Lowy, R. J., Puri, A., Elson, H. F., and Dimitrov, D. S.: How viral envelope glycoprotein negotiate the entry of genetic material into the cell. In Verna, R. and Shamoo, A. (Eds.): Rome, Ares-Serono Symposia Publications, 1994, pp. 151-173.

Dimitrov, D. S.: Electroporation and electrofusion of membranes. In Lipowsky, R. (Ed.): Handbook of Physics of Biological Systems. Amsterdam, Elsevier, 1994, pp. 815-863.

Blumenthal, R. and Dimitrov, D. S.: Membrane Fusion. In Hoffman, J. F. and Jamieson, J. C. (Eds.): Handbook of Physiology Section on Cell Physiology. New York, Oxford University Press, 1997, pp. 569-604.

Dimitrov, D. S.: Modeling HIV infection kinetics. In Iyengar, S. S. (Ed.): Computer Modeling of Complex Biological Systems. Boca Raton, CRC Press, 1998, pp. 79-100.

Kohn, K. W. and Dimitrov, D. S.: Mathematical models of cell cycles. In Iyengar, S. S. (Ed.): Computer Modeling of Complex Biological Systems. Boca Raton, CRC Press, 1998, pp. 101-123.

Dimitrov, D. S., Sidorov, I.A., Endo, Y., Igarashi, T., Lempicki, R. A., Kovacs, J. A., Davey, R.T., Lifson, J., Martin, M.A., and Lane, H. C.: Dynamic models of virus/cell turnover in HIV infections. Proc. Atl. Symp. Comput. Biol. Genome Information Systems and Technology (CBGIST 2001), Eds. Wu, C.H., Wang, P.P, Wang, J.T.L., Durham, 2001, pp. 200-204.

 

BOOKS

Dukhin, S. S., Rulyov, N. N., Dimitrov, D. S.: Coagulation and dynamics of thin layers. Kiev, Publishing House Naukova Dumka, 1986, 232 pp.

Dimitrov, D. S. and Broder, C. C.: HIV and membrane receptors. Austin, Landes Bioscience, Chapman & Hall, Springer, 1997, 190 pp.