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| About TRiPE
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 The T.rex
International
Palaeontonomics Experiment is a consortium set up to
investigate the remarkable
finds made at the Wellcome Trust Genome Campus
during
building excavations in 2002.
Ensembl works
closely
with both TRiPE and other T.rex sequencing groups to
provide
an integrated resource. |
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| T.rex Genome
Assembly (1
Apr 2003) |
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This site proudly presents the first
T.rex draft
assembly. This is based principally on whole genome
shotgun of
around 7x coverage from the sample GRR/ARG, recovered
from the
Hinxton Campus. The assembly consists of large
supercontigs
aligned to chromosomes using a Monte Carlo heuristic.
The
supercontigs are extremely long; this is believed to
be due to
the large size of the organism.
The sequencing
was
entirely funded by the TRiPE consortium. It was
carried out at
laboratories worldwide, using an revolutionary new
technique
that enabled the work to be carried out with a high
degree of
speed and/or precision. See the official Press
Release
for more details.
Since T.rex is a completely
new
genome sequence its annotation is quite limited at
present,
with gene names in most cases taken from the
extremely close
protein homologies to other organisms.
There
are a few
notable exceptions, where early mutational analysis
has
suggested putative gene functions, covering such
phenotypic
traits as colour and size, and even some behavioural
traits. A
number of these annotations are discussed in the Preliminary Annotation
Notes.
We will continue to improve the assembly and
annotation over the coming months, and have scheduled
a second
assembly for the same time next year.
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Assembly Press
Release
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T.rex hinxtonii Discovery Press
Release
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Preliminary Annotation
Notes.
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Credits for the T.rex project can be found here. |
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Assembly statistics |
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Note that the apparent
blurring of the karyotype is caused by DNA degradation due
to the 65
million years the sample spent underground.
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| The Discovery |
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 "Last year's discovery of
long-lost
dinosaur remains in Cambridgeshire astonished the
scientific
community. The remains, most notably those of a
Tyrannosaurus
rex, were found on the Wellcome Trust Genome Campus
whilst
preparations were underway for the construction of an
extension to the site..." [2002
Press
Release] |
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