Proposed JMB cover (it was not accepted)

A quantitative model of ribosome binding uniformly accounts for the statistics of the Shine-Dalgarno, the initiation region and the variable spacing between them. Two sequence logos are shown for the Shine-Dalgarno and initiation region of E. coli ribosome binding sites. They are separated by a histogram depicting the frequency of different distances between the two parts. In combination these three components represent a flexible model for ribosome binding sites. Remarkably, the Shine-Dalgarno matches the 3' end of the 16S rRNA depicted below it as 5' A U U C C U C C 5'. This figure was proposed as the JMB cover but was not accepted.

A quantitative model of ribosome binding uniformly accounts for the statistics of the Shine-Dalgarno, the initiation region and the variable spacing between them.

The original postscript can be rotated and converted to a tif using this ImageMagick command: 

convert -rotate 90 -crop 0x0+10+10 -density 300 -geometry 24% jmbcover.ps jmbcover.tif

Tom Schneider toms@ncifcrf.gov

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Schneider Lab
origin: 2001 Aug 27
updated: 2002 March 31
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