\relax \bibstyle{openmind} \citation{Schneider.Zen2002} \citation{Box1979} \citation{Day.McMorris1992} \citation{Barrett.Sober1991,Nelson1993,Barrett.Sober1993,deQueiroz1993} \citation{Schneider.oxyr,Zheng.Storz.oxyrfur1999} \citation{Lewin1997} \citation{Pribnow1975} \citation{Lisser1993} \citation{Schneider.ev2000} \citation{Shannon1948,Schneider1986,SchneiderPrimer} \citation{Papp.helixrepa,Schneider.oxyr,Schneider.baseflip.2001} \citation{Stephens.Schneider.Splice} \citation{Stephens.Schneider.Splice} \citation{Schneider.walker,Schneider.ri} \citation{Shannon1948} \citation{Stephens.Schneider.Splice} \citation{Rogan.Faux.Schneider1998} \citation{Schneider.ri} \citation{Schneider.Mastronarde.malign} \citation{Hengen.fisinfo} \citation{Slany.Kersten1992} \citation{Hubner1989b} \citation{Hengen.fisinfo} \citation{Kuhn1970} \citation{Rogan.Schneider.hmsh2.1995} \citation{Fishel1993} \citation{Leach1993} \citation{Papp.helixrepa} \citation{PappChattoraj1994} 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\bibcite{Cheng.Kumar1993}{Cheng {\em et\nobreakspace {}al.}, 1993} \bibcite{Day.McMorris1992}{Day \& McMorris, 1992} \bibcite{deQueiroz1993}{de\nobreakspace {}Queiroz, 1993} \bibcite{Eagleman.Sejnowski2000}{Eagleman \& Sejnowski, 2000} \bibcite{Fishel1993}{Fishel {\em et\nobreakspace {}al.}, 1993} \bibcite{Gueron.Leroy1987}{Gu\'{e}ron {\em et\nobreakspace {}al.}, 1987} \bibcite{Hengen.fisinfo}{Hengen {\em et\nobreakspace {}al.}, 1997} \bibcite{Hubner1989b}{{H\"{u}bner} \& Arber, 1989} \bibcite{Kendrick.Baldwin1987}{Kendrick \& Baldwin, 1987} \bibcite{Klimasauskas1994}{Klima\v {s}auskas {\em et\nobreakspace {}al.}, 1994} \bibcite{Kuhn1970}{Kuhn, 1970} \bibcite{Leach1993}{Leach {\em et\nobreakspace {}al.}, 1993} \bibcite{Leroy.Gueron1988}{Leroy {\em et\nobreakspace {}al.}, 1988} \bibcite{Lewin1997}{Lewin, 1997} \bibcite{Lisser1993}{Lisser \& Margalit, 1993} \bibcite{Lyakhov.Schneider2001}{Lyakhov {\em et\nobreakspace {}al.}, 2001} \bibcite{Miller1955}{Miller, 1955} 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\citation{Schneider.walker} \citation{Schneider.baseflip.2001} \citation{Lisser1993} \citation{Schneider.baseflip.2001} \@writefile{lof}{\contentsline {figure}{\numberline {1}{\ignorespaces Sequence logos \cite {Schneider.Stephens1990} for human donor and acceptor splice junctions \cite {Stephens.Schneider.Splice} compared to the consensus sequence for both sites. Source: Adapted from \cite {Stephens.Schneider.Splice}. }}{21}} \newlabel{fig.splicelogo}{{1}{21}} \@writefile{lof}{\contentsline {figure}{\numberline {2}{\ignorespaces Sequence walkers \cite {Schneider.walker} for a human acceptor site in the iduronidase synthetase gene and a mutation (indicated by an arrow). On the top sequence, the normal end of exon 4 is shown by a bracket and dashed line. The vertical rectangle on a sequence walker is the `zero base' used to identify the location of the walker. The vertical rectangles also indicate a scale from $-3$ to $+2$ bits. A 12.7 bit acceptor at 5154 directs splicing to the correct location. Source: Adapted from \cite {Rogan.Faux.Schneider1998}.}}{22}} \newlabel{fig.walker}{{2}{22}} \@writefile{lof}{\contentsline {figure}{\numberline {3}{\ignorespaces Sequence logo for random sequences.}}{23}} \newlabel{fig.random}{{3}{23}} \@writefile{lof}{\contentsline {figure}{\numberline {4}{\ignorespaces Region upstream of the \emph {tgt/sec} promoter of \emph {E. coli} analyzed by Fis sequence walkers. The information for each Fis site was computed from models that are 21 bases wide ($-10$ to $+10$) but only the range $-7$ to $+7$ is shown by walkers. The sine waves represent major (peaks) and minor (valley) grooves faced by the Fis protein. Source: Adapted from \cite {Schneider.walker}. }}{24}} \newlabel{fig.tgtsec}{{4}{24}} \@writefile{lof}{\contentsline {figure}{\numberline {5}{\ignorespaces Sequence logo for RepA binding sites.}}{25}} \newlabel{fig.repalogo}{{5}{25}} \@writefile{lof}{\contentsline {figure}{\numberline {6}{\ignorespaces Sequence logo for the $-10$ region of \emph {E. coli} promoters.}}{26}} \newlabel{fig.minusten}{{6}{26}} \@writefile{lof}{\contentsline {figure}{\numberline {7}{\ignorespaces Consensus \emph {versus} $R_{sequence}$.}}{27}} \newlabel{fig.rsco}{{7}{27}} \@writefile{lot}{\contentsline {table}{\numberline {1}{\ignorespaces $R_{sequence}$ and consensus information for sequence logos.}}{28}} \newlabel{table.rsco}{{1}{28}}