Thomas D. Schneider Research Biologist National Institutes of Health

National Institutes of Health

National Cancer Institute (NCI-Frederick)

Gene Regulation and Chromosome Biology Laboratory

Molecular Information Theory Group

Building 539, Room 129A

Frederick, Maryland 21702-1201

Phone: 301-846-5581

Fax: 301-846-6911

Email: schneidt@mail.nih.gov

permanent email: toms@alum.mit.edu (use only if first address fails)

permanent URL: http://alum.mit.edu/www/toms

• Official NCI-CCR web page
• NIH Directory
• nih.academia.edu

Biography: Dr. Schneider is a Research Biologist in the Gene Regulation and Chromosome Biology Laboratory, National Cancer Institute, a part of the National Institutes of Health. Dr. Schneider received a B.S. in biology at MIT in 1978 and received his Ph.D. in 1984 from the University of Colorado, Department of Molecular, Cellular and Developmental Biology. His thesis was on applying Shannon's information theory to DNA and RNA binding sites (Schneider1986). He is continuing this work at NIH as a tenured research biologist. Using information theory, the commonly used consensus sequences can now be replaced with two kinds of graphic: sequence logos and sequence walkers. The walkers can be used to predict whether or not splice junction sequence changes are polymorphisms or mutations and in the latter case the severity of the resulting disease. By introducing the relationship between energy and information, Dr. Schneider is also applying the theory to many other molecular systems.

• Introduction to using information theory to study binding sites
• Resume
• Tenure project description
• Bibliography
  • Bibliography in BiBTeX format

  • Publications graph

    - with a curious break! I came to NIH in late 1987, so the break might represent the delay to get my stride. Also, 1990 is the date of the publication of sequence logos with my first SIP student, both seminal events. For the doubting Thomases amongst you

    Publications graph, log scale

    On a log scale and it curves down in both parts. I am not capable of exponentially publishing! 8^}
    The gap in publications in 2002 represents a site visit, which cost me about 2 to 3 publications.
  • Current Bibliography in PubMed. This does not include all papers, but does give many abstracts.
  • Current Bibliography in PubMed Central. All of these papers are available online.
• Electronic papers and request form for papers sent by regular mail
• Presentations
• How to arrange talks by Tom Schneider
• Pictures
• Home page: Work
• Lab members
• Visitor information - maps and directions

Schneider Lab
origin: 1997 February 6
updated: 2011 May 24









































            Viewing Files    Accessibility